This one's actually quite subjective, so you'll
need to make the judgment call here.
If you've got a group of new players, they probably won't mind running through a standard 'escape the ancient tomb' storyline. After all, these are only clichés because they're popular!
However, escape room veterans will have come across more mummies, voodoo queens, and vampires than a football game has commercials. The themes are overplayed. Try to find a fresh new idea. Perhaps you could base your game on a heist where the players are the thieves! Think Money Heist, but condensed from a season into 60 minutes.
There's nothing wrong
with using common characters and themes, but try and add just a little bit of your own spin to it. Even a tiny tweak to a clichéd formula can make it feel fresh and exciting!
If you need ideas, try stealing your favorite theme from this list
, and then add one little twist.